Home Transmembrane Transporters Calcium Channel inhibitor Nicardipine For research use only.

Nicardipine

Nicardipine is a potent calcium channel blockader with marked vasodilator action.

Nicardipine Chemical Structure

Nicardipine Chemical Structure

CAS No. 55985-32-5

Purity & Quality Control

Batch: S525501 DMSO]95 mg/mL]false]Ethanol]95 mg/mL]false]Water]30 mg/mL]false Purity: 99%
99

Nicardipine Related Products

Signaling Pathway

Calcium Channel Signaling Pathways

Calcium Channel Signaling Pathway

Biological Activity

Description Nicardipine is a potent calcium channel blockader with marked vasodilator action.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06238011 Not yet recruiting
CABG
Sawanpracharak hospital
 February 28 2024 Not Applicable
NCT05164159 Completed
Acute Cholecystitis
Yonsei University
 February 20 2022 Not Applicable
NCT04137991 Completed
Nociceptive Pain|Goal-directed Therapy|Hemodynamic Instability|Nol-Index|Remifentanil|Cardiac Surgery|Vascular Surgery|General Anesthesia
Erasme University Hospital
 October 10 2019 Not Applicable
NCT01460563 Unknown status
Cerebral Aneurysm
Seoul National University Bundang Hospital
 October 2011 Not Applicable

Chemical Information & Solubility

Molecular Weight 479.52 Formula

C26H29N3O6
CAS No. 55985-32-5 SDF --
Smiles CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 95 mg/mL ( (198.11 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 95 mg/mL

Water : 30 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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