Methylmalonate

Name: Methylmalonate
Brand: Selleck Chemicals
SKU: S3683
Rating: 5 (1 reviews)

Synonyms: Methylmalonic acid, Isosuccinic Acid, NSC 25201, MMA

Catalog No.S3683 Purity:98.89%

Methylmalonate (Methylmalonic acid, Isosuccinic Acid, NSC 25201, MMA) is a dicarboxylic acid that can be derived from methylmalonyl-coenzyme A (methylmalonyl-CoA).

Methylmalonate Chemical Structure

CAS No. 516-05-2

Purity & Quality Control

Batch: S368301 DMSO]23 mg/mL]false]Water]23 mg/mL]false]Ethanol]23 mg/mL]false Purity: 98.89%

98.89

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Related Compound Libraries	FDA-approved Drug Library Natural Product Library Bioactive Compound Library-I Express-Pick Library	Click to Expand

Biological Activity

Description	Methylmalonate (Methylmalonic acid, Isosuccinic Acid, NSC 25201, MMA) is a dicarboxylic acid that can be derived from methylmalonyl-coenzyme A (methylmalonyl-CoA).

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06323538	Not yet recruiting	Dietary Exposure\|Diabetes Mellitus Type 2\|Cardiovascular Diseases\|Bone Loss\|Sustainability\|Exposure\|Obesity\|Vitamin Deficiency\|Mineral Deficiency	German Federal Institute for Risk Assessment\|Max Rubner-Institut\|University of Bonn\|Research Institute for Plant-Based Nutrition\|University of Jena\|University of Regensburg\|Heidelberg University\|University of Vienna	April 1 2024	--
NCT06242483	Not yet recruiting	Hypertension	Hospital Israelita Albert Einstein\|Elfie Pte. Ltd.	April 1 2024	Not Applicable
NCT05949580	Not yet recruiting	Relapsing Remitting Multiple Sclerosis	Hoffmann-La Roche\|icometrix	April 30 2024	--
NCT06117722	Not yet recruiting	Chronic Heart Failure	Elpen Pharmaceutical Co. Inc.	March 1 2024	--

Chemical Information & Solubility

Molecular Weight	118.09	Formula	C₄H₆O₄
CAS No.	516-05-2	SDF	Download Methylmalonate SDF
Smiles	CC(C(=O)O)C(=O)O
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 23 mg/mL ( (194.76 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 23 mg/mL

Ethanol : 23 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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