Manganese chloride

Name: Manganese chloride
Brand: Selleck Chemicals
SKU: S4827
Rating: 5 (1 reviews)

Catalog No.S4827 Purity:98%

Manganese chloride occurs in nature as the mineral. It is used as a precursor for other manganese compounds.

Manganese chloride Chemical Structure

CAS No. 7773-01-5

Purity & Quality Control

Batch: S482701 Water]100 mg/mL]false]DMSO]Insoluble]false]Ethanol]Insoluble]false Purity: 98%

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Biological Activity

Description	Manganese chloride occurs in nature as the mineral. It is used as a precursor for other manganese compounds.

In vitro
In vitro	MnCl2 inhibits proliferation in a dose- and time-dependent manner, induces G0/G1 and S phase arrest and apoptosis in A549 cells^[1].
Cell Research	Cell lines	A549 cells
	Concentrations	0.1, 0.5, 1.0 or 2.0 mM
	Incubation Time	24, 48 or 72 h
	Method	Cells are treated with various concentrations of MnCl2 (0, 0.01, 0.1, 0.5, 1.0 or 2.0 mM) for 24, 48 or 72 h. Cell proliferation is determined with MTT assay and mitotic index measurement and apoptosis is measured by flow cytometer.

References

Chemical Information & Solubility

Molecular Weight	125.84	Formula	MnCl₂
CAS No.	7773-01-5	SDF	--
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

Water : 100 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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