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L-Cystine

L-Cystine is the oxidized dimer form of the amino acid L-cysteine which is a non-essential amino acid of the human body. It is required for wound healing and formation of epithelial tissue.

L-Cystine Chemical Structure

L-Cystine Chemical Structure

CAS No. 56-89-3

Purity & Quality Control

Batch: S480801 0.5MNAOH]6.02 mg/mL]false]DMSO]0.001 mg/mL]false]Water]Insoluble]false Purity: 98%
98

L-Cystine Related Products

Biological Activity

Description L-Cystine is the oxidized dimer form of the amino acid L-cysteine which is a non-essential amino acid of the human body. It is required for wound healing and formation of epithelial tissue.
In vitro
In vitro L-cysteine can enhance proliferation and differentiation of NSCs via the CBS/H2S pathway[1].
Cell Research Cell lines Neural stem cells (NSCs)
Concentrations 0.1, 0.5, 1, 5, 10 and 50 μM
Incubation Time 24 and 48 h
Method NSCs are seeded at 96-well plates and then treated with the indicated concentrations of L-cysteine (L-cys) for 24 and 48 h in reduced growth medium. NSCs proliferation is measured by MTT analysis.
In Vivo
In vivo L-Cysteine dose-dependently decreases food intake in both rats and mice following oral gavage and intraperitoneal administration. L-Cysteine increases neuronal activation in the area postrema and delayed gastric emptying. It suppresses plasma acyl ghrelin levels and does not reduce food intake in transgenic ghrelin-overexpressing mice. Repeated L-cysteine administration decreases food intake in rats and obese mice. L-Cysteine reduces hunger and plasma acyl ghrelin levels in humans[2].
Animal Research Animal Models Male C57BL/6 mice
Dosages 2 mmol/kg
Administration i.p.

Chemical Information & Solubility

Molecular Weight 240.30 Formula

C6H12N2O4S2
CAS No. 56-89-3 SDF --
Smiles C(C(C(=O)O)N)SSCC(C(=O)O)N
Storage (From the date of receipt)

In vitro
Batch:

0.5MNAOH : 6.02 mg/mL

DMSO : 0.001 mg/mL ( (0.0 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble


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In vivo
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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