Home Neuronal Signaling Adrenergic Receptor agonist Isoxsuprine hydrochloride For research use only.

Isoxsuprine hydrochloride

Isoxsuprine hydrochloride is a beta-adrenergic agonist with vasodilator activity.

Isoxsuprine hydrochloride Chemical Structure

Isoxsuprine hydrochloride Chemical Structure

CAS No. 579-56-6

Purity & Quality Control

Batch: S566901 DMSO]68 mg/mL]false]Water]4 mg/mL]false]Ethanol]4 mg/mL]false Purity: 99.89%
99.89

Isoxsuprine hydrochloride Related Products

Signaling Pathway

Adrenergic Receptor Signaling Pathways

Adrenergic Receptor Signaling Pathway

Biological Activity

Description Isoxsuprine hydrochloride is a beta-adrenergic agonist with vasodilator activity.
In Vivo
In vivo In an animal model of transient focal ischemia, isoxsuprine significantly reduces infarct volume compared to vehicle[1].
Animal Research Animal Models Male spontaneously hypertensive rats (SHR)
Dosages 1 mg/kg
Administration IV

Chemical Information & Solubility

Molecular Weight 337.84 Formula

C18H24ClNO3
CAS No. 579-56-6 SDF --
Smiles CC(COC1=CC=CC=C1)NC(C)C(C2=CC=C(C=C2)O)O.Cl
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 68 mg/mL ( (201.27 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 4 mg/mL

Ethanol : 4 mg/mL


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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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