Enapotamab (Anti-AXL / UFO)

Catalog No.A2586 Purity:99%

Enapotamab(Anti-AXL / UFO) is a highly specific rabbit polyclonal antibody that targets receptor tyrosine kinase AXL (UFO). It demonstrates potent activity in immunotherapeutic strategy for the treatment of sarcomas. MW :145.42 KD.

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Purity & Quality Control

Batch: A258601 Purity: 99% Protein concentration: 7.85mg/ml Endotoxin Level: ＜1EU/mg

Choose Selective Axl Inhibitors

Name	Citation	Axl	Others
BMS-777607	58	++++	RON,Met,Tyro3
Bemcentinib (R428)	124	++
XL092	0	+++	VEGFR2,MER,MET
UNC2025	7	+++	FLT3,Mer,TrkA
Ningetinib	0	++++	VEGFR2,c-Met
Tamnorzatinib (ONO-7475)	3	++++	Mer,FLT3
RU-301	0	+
Sitravatinib (MGCD516)	4	++++	DDR2,EPHA3,Mer
CEP-40783 (RXDX-106)	6	+++	c-Met,Tyro3,MER
S49076	1	+++	Met,Mer,FGFR3
Merestinib (LY2801653)	10	+++	DDR1,Met,DDR2
SGI-7079	3	+	YES,Mer,Met
UNC2025 HCl	9	++	Mer,FLT3,Tyro3
Dubermatinib(TP-0903)	17	+
NPS-1034	3	++	Met
LDC1267	9	+	Mer,Tyro3
PF-07265807	✔	Mer

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description	Enapotamab(Anti-AXL / UFO) is a highly specific rabbit polyclonal antibody that targets receptor tyrosine kinase AXL (UFO). It demonstrates potent activity in immunotherapeutic strategy for the treatment of sarcomas. MW :145.42 KD.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1912423-61-0
Molecular Weight	145.42 kDa
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100mMPro-Ac,20mMArg-Ac，pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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