Home GPCR & G Protein Histamine Receptor antagonist Azelastine For research use only.

Azelastine

Synonyms: Azelastina, Astelin

Azelastine(Azelastina; Astelin) is a potent antihistaminic and antiallergic drug, an antagonist of the histamine H1 receptor. It is also effective in treating allergic rhinitis, bronchial asthma, and SARS-CoV-2 and has shown potential in ameliorating aortic calcification, increasing apoA expression, and reducing apoB levels.

Azelastine Chemical Structure

Azelastine Chemical Structure

CAS No. 58581-89-8

Purity & Quality Control

Batch: E492101 DMSO]76 mg/mL]false]Ethanol]38 mg/mL]false]Water]Insoluble]false Purity: 99.51%
99.51

Azelastine Related Products

Signaling Pathway

Histamine Receptor Signaling Pathways

Histamine Receptor Signaling Pathway

Biological Activity

Description Azelastine(Azelastina; Astelin) is a potent antihistaminic and antiallergic drug, an antagonist of the histamine H1 receptor. It is also effective in treating allergic rhinitis, bronchial asthma, and SARS-CoV-2 and has shown potential in ameliorating aortic calcification, increasing apoA expression, and reducing apoB levels.
Targets
Histamine H1 receptor [1]

Chemical Information & Solubility

Molecular Weight 381.90 Formula

C22H24ClN3O
CAS No. 58581-89-8 SDF Download Azelastine SDF
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 76 mg/mL ( (199.0 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 38 mg/mL

Water : Insoluble


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In vivo
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In vivo Formulation Calculator

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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