Home NF-κB NF-κB chemical Vanillylacetone For research use only.

Vanillylacetone

Synonyms: NSC 15335

Vanillylacetone (NSC 15335) is similar in chemical structure to other flavor chemicals such as vanillin and eugenol and is used as a flavor additive in spice oils and in perfumery to introduce spicy aromas. Vanillylacetone (Zingerone) alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways. Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells.

Vanillylacetone Chemical Structure

Vanillylacetone Chemical Structure

CAS No. 122-48-5

Purity & Quality Control

Batch: S237101 DMSO]38 mg/mL]false]Ethanol]38 mg/mL]false]Water]10 mg/mL]false Purity: 99.89%
99.89

Vanillylacetone Related Products

Signaling Pathway

NF-κB Signaling Pathways

NF-κB Signaling Pathway

Biological Activity

Description Vanillylacetone (NSC 15335) is similar in chemical structure to other flavor chemicals such as vanillin and eugenol and is used as a flavor additive in spice oils and in perfumery to introduce spicy aromas. Vanillylacetone (Zingerone) alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways. Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells.
Targets
NF-κB [2]
In vitro
In vitro

Vanillylacetone is similar in chemical structure to other flavor chemicals such as vanillin and eugenol. It is used as a flavor additive in spice oils and in perfumery to introduce spicy aromas. Fresh ginger does not contain vanillylacetone; cooking the ginger transforms gingerol, which is present, into vanillylacetone through a retro-aldol reaction. Vanillylacetone is likely the active constituent responsible for the antidiarrheal efficacy of ginger. [1]

Chemical Information & Solubility

Molecular Weight 194.23 Formula

C11H14O3
CAS No. 122-48-5 SDF Download Vanillylacetone SDF
Smiles CC(=O)CCC1=CC(=C(C=C1)O)OC
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 38 mg/mL ( (195.64 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 38 mg/mL

Water : 10 mg/mL


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In vivo
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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