Home Neuronal Signaling Histamine Receptor agonist Lidocaine For research use only.

Lidocaine

Synonyms: Alphacaine

Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.

Lidocaine Chemical Structure

Lidocaine Chemical Structure

CAS No. 137-58-6

Purity & Quality Control

Batch: S135701 DMSO]47 mg/mL]false]Ethanol]47 mg/mL]false]Water]9 mg/mL]false Purity: 99.97%
99.97

Lidocaine Related Products

Signaling Pathway

Histamine Receptor Signaling Pathways

Histamine Receptor Signaling Pathway

Biological Activity

Description Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
Targets
Histamine H1 receptor [1]
>32 μM
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06391125 Not yet recruiting
Syphilis Infection|Benzathine Penicillin Adverse Reaction
Washington University School of Medicine
 June 2024 Phase 3
NCT05402293 Not yet recruiting
Acute Pain|Lidocaine|Administration and Dosage
University of Alberta
 April 15 2024 --

Chemical Information & Solubility

Molecular Weight 234.34 Formula

C14H22N2O
CAS No. 137-58-6 SDF Download Lidocaine SDF
Smiles CCN(CC)CC(=O)NC1=C(C=CC=C1C)C
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 47 mg/mL ( (200.56 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 47 mg/mL

Water : 9 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Lidocaine | Lidocaine ic50 | Lidocaine price | Lidocaine cost | Lidocaine solubility dmso | Lidocaine purchase | Lidocaine manufacturer | Lidocaine research buy | Lidocaine order | Lidocaine mouse | Lidocaine chemical structure | Lidocaine mw | Lidocaine molecular weight | Lidocaine datasheet | Lidocaine supplier | Lidocaine in vitro | Lidocaine cell line | Lidocaine concentration | Lidocaine nmr