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Hydrochlorothiazide

Hydrochlorothiazide is a first line diuretic compound of the thiazide class.

Hydrochlorothiazide Chemical Structure

Hydrochlorothiazide Chemical Structure

CAS No. 58-93-5

Purity & Quality Control

Batch: S170801 0.5MNAOH]3 mg/mL]false]DMSO]0 mg/mL]false]Water]0 mg/mL]false Purity: 99.86%
99.86

Hydrochlorothiazide Related Products

Biological Activity

Description Hydrochlorothiazide is a first line diuretic compound of the thiazide class.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04964050 Withdrawn
Healthy Volunteers
GlaxoSmithKline
 April 21 2022 Phase 1
NCT05040880 Completed
Hypertension
HK inno.N Corporation
 July 8 2021 Phase 1
NCT06083116 Completed
Diabetes in Adults
Jiangsu HengRui Medicine Co. Ltd.
 August 28 2019 Phase 1
NCT04197622 Completed
Healthy Volunteers
Parc de Salut Mar
 March 5 2019 Phase 1

Chemical Information & Solubility

Molecular Weight 297.74 Formula

C7H8ClN3O4S2
CAS No. 58-93-5 SDF Download Hydrochlorothiazide SDF
Smiles C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl
Storage (From the date of receipt)

In vitro
Batch:

0.5MNAOH : 3 mg/mL

DMSO : 0 mg/mL ( (0.0 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 0 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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