4-Methylumbelliferyl beta-D-glucopyranoside

Name: 4-Methylumbelliferyl beta-D-glucopyranoside
Brand: Selleck Chemicals
SKU: E4012
Rating: 5 (1 reviews)

Synonyms: MUD

Catalog No.E4012 Purity:99.87%

4-Methylumbelliferyl beta-D-glucopyranoside(MUD) is a β-D-glucoside, is a fluorogenic substrate for β-glucosidase. It is utilized in the assay of beta-glucosidase activity.

4-Methylumbelliferyl beta-D-glucopyranoside Chemical Structure

CAS No. 18997-57-4

Purity & Quality Control

Batch: E401201 DMSO]68 mg/mL]false]Water]2 mg/mL]false]Ethanol]Insoluble]false Purity: 99.87%

99.87

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Related Compound Libraries	FDA-approved Drug Library Natural Product Library Bioactive Compound Library-I Express-Pick Library	Click to Expand

Biological Activity

Description	4-Methylumbelliferyl beta-D-glucopyranoside(MUD) is a β-D-glucoside, is a fluorogenic substrate for β-glucosidase. It is utilized in the assay of beta-glucosidase activity.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06286228	Not yet recruiting	Multiple Myeloma	Siriraj Hospital\|Faculty of Medicine Siriraj Hospital	April 1 2024	--
NCT06082947	Recruiting	Hematopoietic Stem Cell Transplantation\|Hematologic Malignancy	Nationwide Children''s Hospital	December 18 2023	Not Applicable
NCT05419843	Not yet recruiting	Idiopathic Aplastic Anemia\|Severe Aplastic Anemia\|Moderate Aplastic Anemia Requiring Transfusions	Assistance Publique - Hôpitaux de Paris	June 2022	Phase 2
NCT03904134	Active not recruiting	Acute Myeloid Leukemia\|Acute Lymphoblastic Leukemia\|Myelodysplastic Syndromes\|Non-hodgkin Lymphoma\|Hodgkin Lymphoma\|Acquired Aplastic Anemia\|Sickle Cell Disease	Center for International Blood and Marrow Transplant Research\|National Heart Lung and Blood Institute (NHLBI)\|National Cancer Institute (NCI)\|Blood and Marrow Transplant Clinical Trials Network\|National Marrow Donor Program\|Medical College of Wisconsin	June 14 2019	Not Applicable

References

[1] Smitka CM, et al. J Clin Microbiol. 1989 Jan;27(1):203-6.

Chemical Information & Solubility

Molecular Weight	338.31	Formula	C₁₆H₁₈O₈
CAS No.	18997-57-4	SDF	Download 4-Methylumbelliferyl beta-D-glucopyranoside SDF
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 68 mg/mL ( (200.99 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 2 mg/mL

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

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% DMSO + % + % Tween 80 + % ddH₂O

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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