Cervical Cancer

Home Cervical Cancer

Tool Compounds

Modeling Agent
7,12-Dimethylbenz[a]anthracene
N-Nitroso-N-methylurea
Hypoxic Marker
Pimonidazole

Drugs Approved

Bevacizumab
Bleomycin sulfate
Topotecan HCl
Pembrolizumab
Tisotumab vedotin

NCCN Guidelines Recommendations [1]

First-Line Systemic Therapy
Pembrolizumab
Cisplatin
Paclitaxel
Bevacizumab
Topotecan
Subsequent-Line Systemic Therapy
Pembrolizumab
Tisotumab vedotin
Cemiplimab
Paclitaxel
Nab-Paclitaxel
Docetaxel
5-FU
Gemcitabine
Pemetrexed
Topotecan
Vinorelbine ditartrate
Irinotecan

Chemotherapy Regimens

CARBOPLATIN-TAXOL
Carboplatin
Paclitaxel
GEMCITABINE-CISPLATIN
Gemcitabine HCl
Cisplatin

Antiviral Infection

Anti-HPV Infection
Isoprinosine
N-p-Tosyl-L-phenylalanine chloromethyl ketone
Vorinostat
A2ti-1
A2ti-2
Anti-HIV Infection
Doxorubicin (DOX) HCl
Plerixafor
Triciribine
Birinapant
Cenicriviroc

ICIs

PD-1
Pembrolizumab
Dostarlimab
Cemiplimab
Camrelizumab
Sintilimab
Nivolumab
Serplulimab
Balstilimab
PD-L1
Atezolizumab
Durvalumab
Avelumab
Adebrelimab
Sugemalimab
CTLA-4
Nurulimab
Zalifrelimab
Quavonlimab
Ipilimumab
Tremelimumab
TIGHT
Tiragolumab
Vibostolimab
Domvanalimab
Ociperlimab

Anti-Angiogenesis [2]

VEGF
Bevacizumab
Pazopanib
Lapatinib
Brivanib
TKIs
Sunitinib
Imatinib
Angiotensin
Angiotensin II human Acetate
Angiotensin
Azilsartan
Olmesartan

Targeted Therapy (A) [3]

CD44
Bivatuzumab
Angstrom6
ALDH
Disulfiram
Daidzin
NCT-501
Alda 1
CM10
ABCG2
Ko143
RG14620
YHO-13177
KS176
5,7-Dimethoxyflavone
NANOG
Amcasertib
BMI1
PTC-209
PTC-209 HBr
PRT4165
Unesbulin
PTC-028

Targeted Therapy (B) [3]

LGR5
Petosemtamab
OCT3/4
O4I2
O4I1
α-SMA
CCG-222740
Apamin
Vimentin
Withaferin A
KLF4
APTO-253
β-catenin
IWP-2
Laduviglusib
Capmatinib
c-Myc
10058-F4
dBET6
10074-G5

CSCs Marker [3]

NANOG
Amcasertib
KLF4
APTO-253
CD133
Amcasertib
Cd44
Bivatuzumab
Angstrom6
ALDH1
Disulfiram
NCT-501
CM10
ABCG2
Ko143
RG14620
YHO-13177
KS176
5,7-Dimethoxyflavone
BMI1
PTC-209
PTC-209 HBr
PRT4165
Unesbulin
PTC-028
LGR5
Petosemtamab

EMT [3]

BMI1
PTC-209
PTC-209 HBr
PRT4165
Unesbulin
PTC-028
Vimentin
Withaferin A

Compound Library

FDA-approved Anticancer Drug Library
Anti-cancer Compound Library
Anti-cancer Compound Library-Ⅱ
Anti-cancer Metabolism Compound Library
Cambridge Cancer Compound Library
Small Molecule Immuno-Oncology Compound Library
Angiogenesis Related compound Library
PI3K/Akt Inhibitor Library
NF-κB Signaling Compound Library
Stem Cell Signaling Compound Library

References

  • https://jnccn.org/view/journals/jnccn/21/12/article-p1224.xml
  • https://www.tandfonline.com/doi/full/10.2147/OTT.S68286
  • https://pubmed.ncbi.nlm.nih.gov/31516560/